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Authors: Luisa Di Paola,† Micol De Ruvo,‡ Paola Paci,‡ Daniele Santoni,§ and Alessandro Giuliani^*,||
†Faculty of Engineering, Università CAMPUS BioMedico, Via A. del Portillo, 21, 00128 Roma, Italy

‡BioMathLab, §CNR-Institute of Systems Analysis and Computer Science (IASI), viale Manzoni 30, 00185 Roma, Italy

||Environment and Health Department, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Roma, Italy

1. Introduction

Topology is at the very heart of chemistry. This stems from the fact that chemical thought, since its prescientific alchemic origins, focused on the mutual relations between different entities expressed in terms of natural numbers instead of continuous quantities. This is the case in the concept of valence (e.g., atomic species A combines with atomic species B in the ratio 1:2 or 2:3) as well as of the periodic table, in which the discrete character of the atoms is implicit in the very same structure of a two-entry (period and group) matrix.¹

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During the last 10 years, the conference on ‘Steroids and Nervous System’ held in Torino (Italy) has been an important international point of discussion for scientists involved in this exciting and expanding research field.

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Heidelberg, 5 December 2012 - We all have E.coli bacteria in our gut but each of us carries a version that is genetically slightly different. The same can be said of most gut microbes: our own gut metagenome, that is the sum of all the genomes of all our gut microbes, appears to be really specific to each of us, and to remain stable over time.

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New Worldwatch Institute report examines the role that sustainable agriculture can play in mitigating the effects of climate change

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The 13th IEEE International Conference on Nanotechnology will be held in Beijing, China, August 5th to 8th, 2013, following successful conferences held in Maui (2001), Washington D.C. (2002), S. Francisco (2003), Munich (2004), Nagoya ( 2005), Cincinnati (2006), Hong Kong (2007), Arlington (2008), Genoa (2009), Seoul (2010) , Portland (2011), Birmingham (2012).

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The most detailed analysis to date of how well rich nations have kept promises to provide poorer ones with funds to tackle climate change was released today. The research concludes that they have collectively failed to fulfil eight substantive pledges.

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Authors:
Amaya Alzu, Alessandra Brambati and Giordano Liberi (IFOM Foundation of Milan and Institute of Molecular Genetics of Italian National Research Council of Pavia).
Abstract
Mutations in Senataxin gene cause two severe neurodegenerative disorders, the Ataxia with oculomotor apraxia type 2 (AOA2) and the juvenile Amyotrophic Later Sclerosis 4 (ALS4). Our study published in Cell (Alzu et al., 2012) unravels a new molecular mechanism that involves Senataxin in preventing DNA damage due to the deleterious consequences of DNA replication-transcription conflicts.

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Grand Challenges Canada awards 68 $100,000 seed grants for bold ideas to tackle disease, save lives in developing countries.

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Dissemination Workshops in France and Poland

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STEP-WISE and STREAM projects are jointly organising their final conference on 3rd-4th December 2012 in Brussels, presenting concrete instruments to facilitate the dialogue between researchers, politicians and research-users.